If you’re looking for a supplement that can help improve your cognitive performance and support your brain health, then you should try a plasmalogen supplement. It has been linked to better memory, focus, and reduces brain fog in older adults.
NeuroPlas Plasmalogen Complex is a brain-health supplement that contains bio-available curcumin. It is patented by Bio-Mer and is known to assist with the breakdown of amyloid plaque build-up which is widely accepted as a leading cause of Alzheimer’s.
Benefits
Plasmalogens are a class of glycerophospholipids that play a vital role in cellular function and health. They are involved in a number of cellular processes including membrane fusion, ion transport, vesicle formation and oxidation-reduction.
They are also anti-inflammatory and help to prevent the build up of amyloid plaques which are a known cause of Alzheimer’s disease. The Plasmalogen Complex in NeuroPlas contains a high dose of Ethanolamine Plasmalogens and is complexed with curcumin which has been shown to assist with the breakdown of amyloid plaque build-up.
Studies have shown that reduced plasmalogen levels are associated with many common degenerative diseases such as cardiovascular disease, hypertension, type 2 diabetes, obesity and cancer. This is why plasmalogen supplementation has been considered a natural solution for those with these conditions.
The current study is the first to evaluate the effects of a specific plasmalogen precursor (DHA-AAG) on lipid metabolism, cognition and mobility in cognitively impaired individuals. The DHA-AAG plasmalogen precursor was administered to the participants in a stepped dose regimen and biomarker analysis was performed at baseline, month 1, and months 2 through 4.
A higher dose of the DHA-AAG plasmalogen precursor increased blood DHA-plasmalogen levels in a dose dependent manner. This was accompanied by an improvement in oxidative stress biomarkers such as malondialdehyde, catalase and superoxide dismutase. Moreover, the participants in the DHA-AAG group showed a statistically significant increase in cognition and mobility.
These results show that a targeted plasmalogen precursor supplementation can improve cognition and mobility in patients with MCI or dementia. This is a promising approach to the treatment of these age-related neurodegenerative disorders.
There are many benefits of using a plasmalogen supplement, however, it is important to know the different types available on the market before making a decision on which one to use. The best plasmalogen supplement is one that contains a high concentration of Ethanolamine Plasmalogens, has been complexed with curcumin and is made from an organic source.
NeuroPlas Plasmalogen Complex is a unique and effective brain-health supplement that has been designed to support and preserve brain function. Each capsule contains 16mg of Ethanolamine Plasmalogens, is complexed with curcumin and is derived from a high-quality organic source. This product has been formulated with the latest research to ensure that it will help to protect brain cells from damage and maintain their normal function.
Dosage
Plasmalogen supplement dosage can vary depending on the nutrient source. Natural sources such as krill, mussels, scallops, and sea squirt can provide high concentrations of plasmalogens. However, they cannot feasibly deliver high enough doses to be effective for human consumption. They also require an enormous amount of raw material to obtain a dietary dose of plasmalogens. For example, a person with average body weight of 70 kg would have to consume 460 kg of scallops per day in order to get the recommended daily dose of 50 mg/kg of plasmalogen.
A plasmalogen deficiency has been linked to multiple inherited diseases including Zellweger’s syndrome (ZS) and rhizomelic chondrodysplasia punctata (RCDP). A reduction in plasmalogen levels has also been associated with many common aging-related neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS).
As plasmalogens are important lipids in the brain, their decline is closely linked with cognitive problems such as dementia, AD, and PD. In addition, they are critical to the formation of lipid rafts and vesicular fusion. These lipids help protect the central nervous system from oxidative stress and are required for synaptogenesis, myelination, and ion transport.
In addition to their critical role in the brain, plasmalogens play a crucial role in the immune system and in other major organ systems. They can scavenge two oxidative species and have been found to protect against inflammation. In addition, they have been shown to protect against age-related changes in DNA and RNA.
The synthesis of plasmalogens involves four biochemical reactions. First, 1-acyl-dihydroxyacetone phosphate (ADHAP) is produced in the peroxisome. The phosphorylated ADHAP is then delivered to the endoplasmic reticulum (ER) where it undergoes further biochemical reactions. These reactions lead to the production of 1-alkyl-2-lyso-sn-glycerol (AGP) and 4-hydroxy-sn-glycerol-4-phosphate (HGP). Upon delivery to the ER, AGP undergoes biochemical reactions that produce PE-Pls and PC-Pls. The enzymes Gnpat and Pex7 are essential for the formation of PE-Pls and PC-Pls, respectively.
In addition to these important fatty acids, plasmalogens are also rich in the nutrients DHA and oleoyl. DHA and oleoyl are both critical for the development and maintenance of brain tissue.
Side effects
Plasmalogens are a class of phospholipids that are important for brain and heart health. They are anti-inflammatory, provide antioxidants, and help maintain optimal lipid levels. They also play a role in cell membranes and cellular function.
They can be found in high concentrations in the human brain and cardiovascular system. This makes them an important component of a healthy diet and can be found in foods such as fatty fish and sardines.
Decreased plasmalogen levels are associated with several degenerative and metabolic diseases including respiratory disorders, cancer, and Alzheimer disease. This is likely due to a combination of chronic inflammation, decreased synthesis, and oxidative stress.
This is why it is important to supplement with a high quality, natural supplement such as NeuroPlas. This is a unique formula that contains a powerful blend of brain-boosting ingredients, including curcumin and plasmalogens.
It has been scientifically proven to improve memory and sharpen cognitive function, and it is available for purchase on Daiwa’s website. It is a safe and effective way to support brain health.
Researchers have shown that plasmalogens can increase blood and brain levels of a protein called C-Reactive Protein (CRP). This is thought to be a factor in cognitive impairment, and may be a possible treatment option for patients who are prone to developing dementia or Alzheimer’s.
The study was a randomized, double-blind, placebo-controlled trial conducted over 24 weeks. 328 elderly patients were divided into two groups: the first received 1 mg of Pls purified from scallop daily, and the second received a placebo. Participants were measured at the start of the study and after 24 weeks on a number of tests, including the Mini Mental State Examination-Japanese (MMSE-J), Geriatric Depression Scale-Short Version-Japanese (GDS-S-J), and Wechsler Memory Scale-Revised (WMS-R).
The results showed that the group taking Pls improved significantly in both the 0 min and 30 min tests, while no changes were seen in the placebo group. This is an encouraging finding, especially considering that the results were backed up by other studies. The results are similar to those of another recent study, which shows that plasmalogen supplementation improves cognition in mild Alzheimer’s patients.
Sources
Plasmalogens are phospholipids that are important for a variety of different biological processes. They also have many beneficial effects on health, including improving cognitive function and promoting brain health. However, their levels are reduced in many degenerative and metabolic disorders and during aging.
In most cases, decreased plasmalogen levels lead to an increase in inflammation and other pathological symptoms. Therefore, a plasmalogen supplement can be effective in reversing these issues.
The main sources of plasmalogens are dietary supplements and natural sources of these lipids. They are found in high levels in seafood such as krill, mussels, and sea squirt as well as land animals such as pork, beef, and chicken.
According to Bozelli and Epand, plasmalogens can be a useful nutrient for human health because they have been shown to improve cognitive function in animal models of various diseases. This is due to the fact that they are able to support membrane fluidity, which plays an important role in information processing in the brain.
They are also considered to be beneficial because they have the ability to protect against oxidative stress. The unique structure of the lipids allows them to scavenge two reactive oxygen species, preventing cellular damage.
Additionally, plasmalogens have been shown to enhance ATP production and improve cell membrane stability. Moreover, they can increase cholesterol transport and promote vesicular fusion.
Increasing the levels of these lipids in the body can be accomplished by eating a diet rich in protein and omega-3 fatty acids, such as fish or mollusks. The o-6 to o-3 fatty acid ratio in these foods is also lower, which may help reduce the risk of heart disease.
In addition, shark liver oil is an excellent source of alkylglycerols that can be metabolized into plasmalogens. It has been shown to reduce serum cholesterol and phospholipid concentrations in obese subjects, and it can increase PlsEtns and PC-Pls in mice.
Increasing the level of these lipids in the body can help improve symptoms of a number of metabolic diseases, including diabetes, cardiovascular disease, hypertension, and cancer. They have also been found to promote remyelination in the brain, which is important for improving neuronal function. In addition, they can be a valuable tool for treatment-resistant cancer patients since they can inhibit the growth of tumor cells by reducing lipid peroxidation and ferroptosis.